A Chirality-Based Quantum Leap

There is increasing interest in the study of chiral degrees of freedom occurring in matter and in electromagnetic fields. Opportunities in quantum sciences will likely exploit two main areas that are the focus of this Review: (1) recent observations of the chiral-induced spin selectivity (CISS) effect in chiral molecules and engineered nanomaterials and (2) rapidly evolving nanophotonic strategies designed to amplify chiral light-matter interactions. On the one hand, the CISS effect underpins the observation that charge transport through nanoscopic chiral structures favors a particular electronic spin orientation, resulting in large room-temperature spin polarizations. Observations of the CISS effect suggest opportunities for spin control and for the design and fabrication of room-temperature quantum devices from the bottom up, with atomic-scale precision and molecular modularity. On the other hand, chiral-optical effects that depend on both spin- and orbital-angular momentum of photons could offer key advantages in all-optical and quantum information technologies. In particular, amplification of these chiral light-matter interactions using rationally designed plasmonic and dielectric nanomaterials provide approaches to manipulate light intensity, polarization, and phase in confined nanoscale geometries. Any technology that relies on optimal charge transport, or optical control and readout, including quantum devices for logic, sensing, and storage, may benefit from chiral quantum properties. These properties can be theoretically and experimentally investigated from a quantum information perspective, which has not yet been fully developed. There are uncharted implications for the quantum sciences once chiral couplings can be engineered to control the storage, transduction, and manipulation of quantum information. This forward-looking Review provides a survey of the experimental and theoretical fundamentals of chiral-influenced quantum effects and presents a vision for their possible future roles in enabling room-temperature quantum technologies.ISSN:1936-0851ISSN:1936-086

Topological dispersion relations in spin-orbit coupled Bose gases

Quantum degenerate gases have proven to be an ideal platform for the simulation of complex quantum systems. Due to their high level of control it is possible to readily design and implement systems with effective Hamiltonians in the laboratory. This thesis presents new tools for the characterization and control of engineered quantum systems and describes their application in the realization of a topological system with Rashba-type spin-orbit coupling. The underlying properties of these engineered systems depend on their underlying energies. I describe a Fourier transform spectroscopy technique for characterizing the single particle spectrum of a quantum system. We tested Fourier spectroscopy by measuring the dispersion relation of a spin-1 spin-orbit coupled Bose-Einstein condensate (BEC) and found good agreement with our predictions. Decoherence due to uncontrolled fluctuations of the environment presents fundamental obstacles in quantum science. I describe an implementation of continuous dynamical decoupling (CDD) in a spin-1 BEC. We applied a strong radio-frequency (RF) magnetic field to the ground state hyperfine manifold of Rubidium-87 atoms, generating a dynamically protected dressed system that was first-order insensitive to changes in magnetic field. The CDD states constitute effective clock states and we observed a reduction in sensitivity to magnetic field of up to four orders of magnitude. We additionally show that the CDD states can be coupled in a fully connected geometry and thus enable the implementation of new models not possible using the bare atomic states. Finally, I describe a new realization of Rashba-type SOC using Raman coupled CDD states. Our system had non-trivial topology but no underlying crystalline structure that yields integer valued Chern numbers in conventional materials. We validated our procedure using Fourier transform spectroscopy to measure the full dispersion relation containing only a single Dirac point. We measured the quantum geometry underlying the dispersion relation and obtained the topological index using matter-wave interferometry. In contrast to crystalline materials, where topological indices take on integer values, our continuum system reveals an unconventional half-integer Chern number

Consenso de expertos colombianos sobre recomendaciones basadas en evidencia para el diagnóstico, tratamiento y seguimiento del raquitismo hipofosfatémico ligado al cromosoma X (RHLX)

Background: X-linked hypophosphatemic rickets is a hereditary disease that generates alterations in bone mineral homeostasis. The morbidity of the condition has been variable in previous decades and even contradictory, probably due to the definition of the case and the diagnostic confirmation. Our propose was to generate evidence-informed recommendations for the diagnosis, treatment, and follow-up of patients with suspected or diagnosed XLHR. Results: After the screening and selection process for 1041 documents, 38 were included to answer the questions raised by the developer group. 97 recommendations about the diagnosis, treatment, and follow-up of patients with suspected or diagnosed XLHR were approved by the experts consulted through modified Delphi consensus. The quality of the evidence was low. Conclusions: The recommendations proposed here will allow early and timely diagnosis of X-linked hypophosphatemic rickets, while optimizing resources for its treatment and follow-up and help clarify the burden of disease and improve health outcomes for this population

A Chirality-Based Quantum Leap

Chiral degrees of freedom occur in matter and in electromagnetic fields and constitute an area of research that is experiencing renewed interest driven by recent observations of the chiral-induced spin selectivity (CISS) effect in chiral molecules and engineered nanomaterials. The CISS effect underpins the fact that charge transport through nanoscopic chiral structures favors a particular electronic spin orientation, resulting in large room-temperature spin polarizations. Observations of the CISS effect suggest opportunities for spin control and for the design and fabrication of room-temperature quantum devices from the bottom up, with atomic-scale precision. Any technology that relies on optimal charge transport, including quantum devices for logic, sensing, and storage, may benefit from chiral quantum properties. These properties can be theoretically and experimentally investigated from a quantum information perspective, which is presently lacking. There are uncharted implications for the quantum sciences once chiral couplings can be engineered to control the storage, transduction, and manipulation of quantum information. This forward-looking perspective provides a survey of the experimental and theoretical fundamentals of chiral-influenced quantum effects, and presents a vision for their future roles in enabling room-temperature quantum technologies